Dr Kendelle Murphy is a Group Leader in the Cancer Ecosystems Program at the Garvan Institute of Medical Research. She undertook her undergraduate studies at the University of Western Australia, before moving the Garvan Institute for her honours project and subsequent PhD. As CINSW Early Career Fellow alumni, Dr Murphy continues to conduct research with a clear focus on clinical translation. Cancer develops in a complex three-dimensional environment, where tumour cell communication with the surrounding stroma governs cancer cell behaviour. Dr Murphy and her team use novel state-of-the-art intravital (in vivo, ACRF INCITe Centre) imaging approaches to provide new insights into how cells behave in a physiologically relevant environment, thereby improving our understanding of disease progression, drug delivery and efficacy.