Programme
09:15 - 09:30
Registration
16:00 - 18:30
Champalimaud Auditorium
Welcome / Introduction
Advances in Pancreatic Cancer Treatment
Coffee Break
Advances in Pancreatic Cancer Treatment (Cont.)
Lunch Break
Cell plasticity and tumor heterogeneity
Developing Standards
International Study Group of Pancreatic Surgery (ISGPS)*
Coffee Break
Surgery vs wait and see: PanNET’s and IPMN
Surgery for Locally Advanced PDAC
09:15 - 09:30
Welcome Introduction
08:30 - 09:00
Champalimaud Auditorium
- Leonor Beleza, Lisbon, Portugal
- João Silveira Botelho, Lisbon, Portugal
- Peter Bailey, Lisbon, Portugal
09:15 - 09:30
Keynote Lecture
09:00 - 09:30
Champalimaud Auditorium
- Markus Büchler, Lisbon, Portugal
09:15 - 09:30
Borderline / Locally Advanced PDAC - Diagnosis and Non-Surgical Treatment
09:30 - 10:50
Champalimaud Auditorium
Chairs:
- Jérôme Cros, France
- Celso Matos, Lisbon, Portugal
- Grainne O’Kane, Dublin, Ireland
- Wolfram Zoller
09:30 - 09:50
Clinical Trials: Overview
Eileen O’Reilly, New York, USA
09:50 - 10:10
Imaging: CT, MRI and PET
Götz Richter, Lisbon, Portugal
10:10 - 10:30
Neoadjuvant Treatment Standards
Carlos Carvalho, Lisbon, Portugal
10:30 - 10:50
KRAS Trials
Christoph Springfeld, Heidelberg, Germany
09:15 - 09:30
Borderline / Locally Advanced PDAC Surgery (1)
09:45 - 11:05
Botton Auditorium
Chairs:
- Cristina Ferrone, Los Angeles, USA
- Helmut Friess, Munich, Germany
- Michael Ghadimi, Goettingen, Germany
- Ugo Boggi, Pisa, Italy
09:45 - 10:05
Biology to Define Resectability
Christopher Wolfgang, New York, USA
10:05 - 10:25
It’s all About Vascular Surgery
Thilo Hackert, Hamburg, Germany
10:25 - 10:45
How Much Neoadjuvant Chemotherapy?
Elena Rangelova, Gothenburg, Sweden
10:45 - 11:05
Artery First
Martin Loos, Heidelberg, Germany
09:15 - 09:30
Coffee Break
11:00 - 11:30
09:15 - 09:30
ISGPS Session
11:30 - 12:50
Seminar Room
Chairs:
- Giovanni Marchegianni, Padova, Italy
11:30 - 11:40
PPH Meeting
Filipe Borges, Lisbon, Portugal
11:40 - 11:50
Ischemia after DP-CAR - Proposal for Definition
Vera Oliveira, Lisbon, Portugal
11:50 - 12:00
Extent of Resection - Proposal for a Grading
Miguel Fróis Borges, Lisbon, Portugal
12:00 - 12:10
Arterial Divestment - Proposal for a Definition
Filipe Borges, Lisbon, Portugal / Jishu Wei, Nanjing, China
12:10 - 12:20
DGE Update Proposal?
TBA
12:20 - 12:30
Post Pancreatectomy Diarrhea Update
TBA
09:15 - 09:30
Translational / Oncology (1)
11:30 - 13:10
Champalimaud Auditorium
Chairs:
- Eileen O’Reilly, New York, USA
- Wungki Park, New York, USA
- Maxim Pimkin, Boston, USA
- Dieter Saur, France
11:30 - 11:50
Modelling Tumour Evolution
Roland Rad, München, Germany
11:50 - 12:10
LAPNet1 Clinical Trial
Gael Roth, Grenoble, France
12:10 - 12:30
Vascular Invasion
Pelin Bagci, Lisbon, Portugal
12:30 - 12:50
PANOVA-3
Teresa Macarulla, Barcelona, Spain
12:50 - 13:10
Combination of Cancer Vaccine, Pembrolizumab, and Stereotactic Body Radiation in Patients with Locally Advanced Pancreatic Cancer
Lei Zheng, Maryland, USA
09:15 - 09:30
Borderline / Locally Advanced PDAC Surgery (2) - Minimally Invasive
11:30 - 13:10
Botton Auditorium
Chairs:
- Paulo Costa, Lisbon, Portugal
- Yi Miao, Nanjing, China
- Amer Zureikat, USA
11:30 - 11:50
The Doha Approach
Mohammed Al-Saeedi, Doha, Qatar
11:50 - 12:10
The Chinese Approach
Bayong Shen, Shanghai, China
12:10 - 12:30
Robotic Vascular Reconstruction
Ugo Boggi, Pisa, Italy
12:30 - 12:50
The Korean Approach
Jin-Young Jang, Seoul, South Korea
12:50 - 13:10
Pancreatic Left Resection
Gil Gonçalves, Lisbon, Portugal
09:15 - 09:30
Lunch Break
13:10 - 14:00
09:15 - 09:30
Borderline / Locally Advanced PDAC Surgery (3)
14:00 - 15:40
Champalimaud Auditorium
Chair:
- Giovanni Marchegiani, Padova, Italy
- Charles Vollmer, Philadelphia, USA
- Christopher Wolfgang, New York, USA
- Shailesh Shrikhande, Mumbai, India
14:00 - 14:20
How to Avoid Local Recurrence
Marco Del Chiaro, Denver, USA
14:20 - 14:40
Venous Involvement: High Resectability
Filipe Borges, Lisbon, Portugal
14:40 - 15:00
Multivisceral Resection
Beat Müller, Basel, Switzerland
15:00 - 15:20
Multivascular Resection
Philippe Bachellier, Strasbourg, France
15:20 - 15:40
How to Avoid Vascular Resection
Carlos Fernandéz-Del Castillo, Boston, USA
09:15 - 09:30
Early Career Researchers (1) - Wurth
14:00 - 16:20
Botton Auditorium
Chairs:
- Nelson Dusetti, Marseille, France
- Francisco Real, Madrid, Spain
- Federica Valsecchi, Brescia, Italy
14:00 - 14:20
Therapeutic Vaccination in Pancreatic Cancer: Dendritic Cells and Personalized Neoantigens
Dutch Representative: Casper van Eijck, Amsterdam, Netherlands
14:20 - 14:40
Amoeboid Escape from Premalignant Lesions Drives Early Metastatic Dissemination in Pancreatic Cancer
Italian Representative: Andrea Costamagna, Torino, Italy
14:40 - 15:00
From ER Stress to PDAC: Impact of the CTRB2 Exon 6 Deletion Variant
Spanish Representative: Irene Felipe Abrio, Madrid, Spain
15:00 - 15:20
Trogocytosis-Dependant Lipid Transfer Between Pancreatic Fibroblasts and Cancer Cells: Role of the Phospholipide Scramblase ANO6
French Representative: Charline Ogier, Toulouse, France
15:20 - 15:40
Pre-Existing Intratumoral Programs Constrain Therapeutic Adaptation and Resistance Evolution in Pancreatic Ductal Adenocarcinoma
French Representative: Nicolas Fraunhoffer, Marseille, France
15:40 - 16:00
Lung and Liver Metastasis are Distinct Clonal Events in Pancreatic Cancer
German Representative: Johanna Hölken, Essen, Germany
16:00 - 16:20
Integrated Multi-Platform Profiling Reveals KRAS-Dependent Spatial Organization of the Pancreatic Tumor Microenvironment
German Representative: Philipp Putze, Munich, Germany
09:15 - 09:30
Coffee Break
16:20 - 17:00
09:15 - 09:30
Borderline / Locally Advanced PDAC Surgery (4)
16:30 - 18:10
Champalimaud Auditorium
Chairs:
- Marco Del Chiaro, Colorado, USA
- Thilo Hackert, Frankfurt, Germany
- Beat Müller, Basel, Switzerland
16:30 - 16:50
The Risk of Advanced Pancreatic Surgery
Charles Vollmer, Philadelphia, USA
16:50 - 17:10
Technical Options to Replace Vein and/or Artery
Shailesh Shrikhande, Mumbai, India
17:10 - 17:30
The TRIANGLE Operation
Vera Oliveira, Lisbon, Portugal
17:30 - 17:50
Deep Mesenteric Involvement
Giovanni Marchegianni, Padova, Italy
17:50 - 18:10
Arterial Resection vs Divestment
Robert Grützmann, Erlangen, Germany
09:15 - 09:30
Early Career Researchers (2) - PCUK
17:00 - 19:00
Botton Auditorium
Chairs:
- Giulia Biffi, Cambridge, England
- Corinne Bousquet, Toulouse, France
- Francisco Real, Madrid, Spain
17:00 - 17:20
TBA
Portuguese Representative (Botton): TBD, Lisbon, Portugal
17:20 - 17:40
Leveraging Focused Ultrasound (FUS) to Improve Immunotherapy Responses in Pancreatic Cancer
PCUK Representative: Anita Fallah, Oxford, England
17:40 - 18:00
Pancreatic Cancer Risk at the Interface of Peripheral Innervation and Epithelial Regeneration
PCUK Representative: Rute Ferreira, London, England
18:00 - 18:20
Multi-Stromal Organoid Co-Culture Modelling Reveals Epithelial-Fibroblast Heterogeneity in Pancreatic Cancer and Pancreatitis
PCUK Representative: Wenlong Li, Cambridge, England
18:20 -1 8:40
Mechanistic Insights into Irreversible Electroporation in Pancreatic Cancer: Integrating Ex Vivo Human Tissue Perfusion with Translational Models
PCUK Representative: Zainab Rai, London, England
18:40 - 19:00
CARES-AI: A Novel Checklist for Assessing Implementation Readiness in AI Applications – A Case Study in Pancreatic Cancer Early Detection and Diagnosis
PCUK Representative: Tianhui Zhu, London, England
Welcome / Introduction
Advances in Pancreatic Cancer Treatment
Coffee Break
Advances in Pancreatic Cancer Treatment (Cont.)
Lunch Break
Cell plasticity and tumor heterogeneity
Developing Standards
International Study Group of Pancreatic Surgery (ISGPS)*
Coffee Break
Surgery vs wait and see: PanNET’s and IPMN
Surgery for Locally Advanced PDAC
09:15 - 09:30
Breakout Session: Young Pancreatologists Forum
09:00 - 10:30
Seminar Room
Chairs:
- Filipe Borges, Lisbon, Portugal
- Thomas Hank, Heidelberg, Germany
- Greg Sacks, New York, USA
09:00 - 09:15
Arterial Disease in Pancreatic Cancer – Insights from Surgical Specimens
Benedict Kinny-Köster, New York, USA
09:15 - 09:30
TBA
09:30 - 09:45
Pushing the Limits of Resectability in Locally Advanced Pancreatic Cancer
Ingmar Rompen, Heidelberg, Germany
09:45 - 10:00
TBA
Jishu Wei, Nanjing, China
10:00 - 10:15
SPLENDID: Spleen Preservation in left Pancreatectomy for PDAC
Jony Van Hilst, Amsterdam, Netherlands
10:15 - 10:30
ANTIthrombotic Therapy in PANcreatIc Surgery with VasCular Resection: The ANTIPANIC Study
Alessio Marchetti, Padova, Italy
10:30 - 10:45
TBA
Ana João, Lisbon, Portugal
09:15 - 09:30
Surgery for Metastatic PDAC (1)
09:00 - 11:00
Botton Auditorium
Chairs:
- Phillipe Bachellier, Strasbourg, France
- Carlos Fernandéz-del Castillo, Boston, USA
- Pierluigi Di Sebastiano, Chieti, Italy
- Robert Grützmann, Erlangen, Germany
09:00 - 09:20
The German Multicenter Trial
Michael Ghadimi, Goettingen, Germany
09:20 - 09:40
How Many Metastases to Resect?
Helmut Friess, Munich, Germany
09:40 - 10:00
Liver, Lung and More
Waldemar Uhl, Bochum, Germany
10:00 - 10:20
Peritoneal Seeding
Tiago Bouça Machado, Porto, Portugal
10:20 - 10:40
The US Approach
Cristina Ferrone, Los Angeles, USA
09:15 - 09:30
Metastatic PDAC - Oncology
09:00 - 11:00
Champalimaud Auditorium
Chairs:
- Carlos Carvalho, Lisbon, Portugal
- Teresa Macarulla, Barcelona, Spain
- Roland Rad, München, Germany
- Gael Roth, Grenoble, France
09:00 - 09:20
RNA Neoantigen Vaccines
TBA
09:20 - 09:40
POLAR Trial
Wungki Park, New York, USA
09:40 - 10:00
Vaccine Trials
TBA, Maryland, USA
10:00 - 10:20
Population-Based Surgery in Germany
René Mantke, Bradenburg, Germany
10:20 - 10:40
Treatment for Germline BRCA-Mutations in Metastatic Disease
Talia Golan, Ramat Gan, Israel
10:40 - 11:00
PRMT5 Inhibitor Trials
Maxim Pimkin, Boston, USA
09:15 - 09:30
Coffee Break
11:00 - 11:30
09:15 - 09:30
Keynote Lecture
11:00 - 11:30
Botton Auditorium
Chairs:
- Markus Büchler, Lisbon, Portugal
11:00 - 11:30
The Future of Research in Champalimaud Foundation
Otmar Wiestler, Lisbon, Portugal
09:15 - 09:30
Breakout Session: World Pancreas Forum “Multicentric Collaborations for the Advance of Pancreatic Cancer Surgery”
11:30 - 12:30
Seminar Room
Chairs:
- Markus Büchler, Lisbon, Portugal
- Yi Miao, Nanjing, China
- Christopher Wolfgang, New York, USA
11:30 - 11:40
Major Advances from International Collaborations
Pierluigi Di Sebastiano, Chieti, Italy
11:40 - 11:50
International Collaborations for Training
Zipeng Lu, Nanjing, China
11:50 - 12:00
How to Fund Collaborative Research
Thomas Hank, Heidelberg, Germany
12:00 - 12:10
TBA
Miguel Fróis Borges, Lisbon, Portugal
12:10 - 12:20
TBA
Shailesh Shrikhande, Mumbai, India
12:20 - 12:30
The PANC-PALS Example
Greg Sacks, New York, USA
09:15 - 09:30
Metastatic PDAC - Translational
11:30 - 13:10
Champalimaud Auditorium
Chairs:
- Markus Büchler, Lisbon, Portugal
- Grainne O’Kane, Dublin, Ireland
- Nina Steele, Detroit, USA
11:30 - 11:50
Pathways of Dissemination
Peter Bailey, Lisbon, Portugal
11:50 - 12:10
Molecular Signatures of Heterogeneous Response to Chemotherapy in Pancreatic Cancer
Laura Wood, Baltimore, USA
12:10 - 12:30
Locally Advanced Genomes
Faiyaz Notta, New York, USA
12:30 - 12:50
Metastatic Organotropism
Gulam Manji, New York, USA
12:50 - 13:10
Perineural Invasion in the TRIANGLE Region
Giuseppe Diaferia, Lisbon, Portugal
09:15 - 09:30
Surgery for Metastatic PDAC (2)
11:00 - 12:40
Botton Auditorium
Chairs:
- Kuirong Jiang
- Elena Rangelova, Gothenburg, Sweden
- Bayong Shen, Shanghai, China
11:00 - 11:20
Lisbon’s Stage IV Surgical Data
Miguel Borges, Lisbon, Portugal
11:20 - 11:40
Multivisceral Resections
Alexis Ulrich, Neuss, Germany
11:40 - 12:00
The Canadian Approach
George Zogopoulos, Montreal, Canada
12:00 - 12:20
Metachronous Metastasis Surgery
Nuh Rahbari, Ulm, Germany
12:20 - 12:40
Conversion Surgery
Thilo Welsch, Frankfurt, Germany



