Faculty
Hartland Jackson
Dr. Jackson is an Investigator at the Lunenfeld Tanenbaum Research Institute, an Assistant Professor in the Department of Molecular Genetics at the University of Toronto, and the Canada Research Chair in Systems Pathology. Dr. Jackson’s work developed multiplexed imaging technologies and analysis methods to study cell organization within tissue sections. Now, the Jackson lab strives to understand tissues and tumours as the integrated outcome of their single-cell components and studies the spatial heterogeneity of pancreatic cancer as a member of the PanCuRx team as an Investigator at the Ontario Institute of Cancer Research. To do so, his team utilizes and develops multiplexed imaging and spatial technologies to simultaneously quantify single-cell phenotypes and markers of their functional state, as well as their interactions, overall organization, and contribution to tissue architecture. These methods facilitate spatially-resolved screening of distinct clones in mouse models of disease and the identification of cell environments associated with clinical outcomes in biobanked patient tissues.